Introduce
Polydeoxyribonucleotide (PDRN)
Polydeoxyribonucleotide (PDRN) is a highly purified mixture of DNA fragments (polynucleotides), typically extracted from natural sources like salmon milt. It consists of stable deoxyribonucleotide polymers ranging in size from 50 to 1,500 base pairs. PDRN is widely recognized in regenerative medicine and cosmetology as a potent cell activator and tissue repair agent.
Key Applications and Benefits
Tissue Regeneration: Acts as a direct precursor for DNA synthesis, stimulating cell growth and fibroblast activity to accelerate the repair of damaged tissues, including skin, tendons, and cartilage.
Anti-inflammatory Effect: PDRN binds to the Adenosine A2A receptor on cell surfaces, exerting a significant anti-inflammatory action that helps reduce swelling and pain.
Angiogenesis Promotion: It facilitates the formation of new blood vessels (angiogenesis), which improves local blood supply, delivering vital oxygen and nutrients to speed up the healing process.
Cosmetic and Medical Use: Primarily used in aesthetic treatments to improve skin elasticity, texture, and acne scars, and in orthopedics for chronic wound and joint injury repair.
Safety and Quality
PDRN is subject to rigorous purification processes, ensuring high biological safety and excellent biocompatibility. It is a stable compound that has been extensively studied for various clinical and therapeutic applications.